Biochemistry Subspecialty

Biochemistry Publications

Recently Published Manuscripts in International and Local Journals and Conferences

2018 - 2020

# Publisher  Author Title
1 Experimental Biology and Medicine 244(7):545-553. El-Ashmawy N E, Khedr E G, Shamloula M M, and Kamel M M Evaluation of the antirheumatic effects of isoflavone-free soy protein isolate and etanercept in rats with adjuvant-induced arthritis
2 Molecular Biology Reports 45(5):1421-1444. Elshazli R M, Salman D O, Kamel M M, Toraih E A, and Fawzy M S Genetic polymorphisms of IL-17A rs2275913, rs3748067 and IL-17F rs763780 in gastric cancer risk: evidence from 8124 cases and 9873 controls.
3 Nahla E El-Ashmawy, Eman G Khedr, Awad M ElAbd, Amir O Hamouda Association Between Soluble Urokinase Plasminogen Activator Receptor And Interleukin 6 In The Diagnosis Of Coronary Artery Disease Patients
4 Tumor Biology, 4(42): 1010430000000000 Yousef, Eman H; El-Mesery, Mohamed E; Habeeb, Maha R; Eissa, Laila A; Polo-like kinase 1 as a promising diagnostic biomarker and potential therapeutic target for hepatocellular carcinoma

Published manuscripts in international and local journals and conferences

2021 - 2022

# Publisher  Author Title
1 Journal of Advanced Pharmacy Research Helal, Manar; Shawky, Mohamed; Elhusseiny, Shady; Abd Elhameed, Ahmed; Lactoferrin Ameliorates Azithromycin-induced Cardiac Injury: Insight into Oxidative Stress/TLR4/NF-κB Pathway
2 Life Sciences, 279:119673. Elnagar G M, Elseweidy M M, Mahmoud Y K, Elkomy N M, Althafar Z M, Alnomasy S F, Al-Gabri N A, and Shawky M 10-Dehydrogingerdione ameliorates renal endoplasmic reticulum/oxidative stress and apoptosis in alcoholic nephropathy induced in experimental rats.
3 Current Issues in Molecular Biology 43(3):2199-2209. Salahuddin M M, Omran G A, Helmy M W, and Houssen M E Effect of regorafenib on P2X7 receptor expression and different oncogenic signaling pathways in a human breast cancer cell line: a potential of new insight of the antitumor effects of regorafenib.
4 Journal of Advanced Pharmacy Research, 2021, 5 (2), 273-284 Manar G. Helal, Mohamed Shawky, Shady Elhusseiny, Ahmed G. Abd Elhameed Lactoferrin Ameliorates Azithromycin-induced Cardiac Injury: Insight into Oxidative Stress/TLR4 /NF-κB Pathway

Published Manuscripts in International and Local Journals and Conferences

2022 - 2023

# Publisher  Author Title
1 European Review for Medical and Pharmacological Sciences 26(23):8644-8659 Hamouda A, Abdel-Hamed A, Abo-Elmatty D, Khedr N, and Ghattas M Pentoxifylline and its association with kaempferol improve NASH-associated manifestation in mice through anti-apoptotic, anti-necroptotic, antioxidant, and anti-inflammatory mechanisms.
2 Journal of Medicinal and Chemical Sciences 6(5):250-265 Maivel H. Ghattas Asmaa R. Abdel-Hamed, Amir O. Hamouda, Dina M. Abo-elmatty, Naglaa F. Khedr Role of Kaempferol Combined with Pioglitazone in the Alleviation of Inflammation and Modulation of Necroptosis and Apoptosis Pathways in NASH-induced Mice .
3 international Journal of Molecular Sciences 23(3):1384 Elnagar G M, Elseweidy M M, Mahmoud Y K, Elkomy N M, Althafar Z M, Alnomasy S F, Al-Gabri N A, and Shawky M 10-Dehydrogingerdione Attenuates Tramadol-Induced Nephrotoxicity by Modulating Renal Oxidative Stress, Inflammation and Apoptosis in Experimental Rats: Role of HO-1 Activation and TLR4/NF-κB/ERK Inhibition.
4 Cells 11(24):4128. Elnagar G M, Elseweidy M M, Mahmoud Y K, Elkomy N M, Althafar Z M, Alnomasy S F, Al-Gabri N A, and Shawky M Relative Importance of Different Elements of Mitochondrial Oxidative Phosphorylation in Maintaining the Barrier Integrity of Retinal Endothelial Cells: Implications for Vascular-Associated Retinal Diseases. , ...
5 International Journal of Molecular Sciences. 2023;24:4004. Antar SA, Ashour NA, Marawan ME, Al-Karmalawy AA. Fibrosis: Types, Effects, Markers, Mechanisms for Disease Progression, and Its Relation with Oxidative Stress, Immunity, and Inflammation.

Published manuscripts in international and local journals and conferences

2023 - 2024

# Title Author journal
1 Carvacrol enhances anti-tumor activity and mitigates cardiotoxicity of sorafenib in thioacetamide-induced hepatocellular carcinoma model through inhibiting TRPM7 Eman H Yousef, Nada F Abo El-Magd, Amal M El Gayar Life Sciences, -2023
2 Norcantharidin potentiates sorafenib antitumor activity in hepatocellular carcinoma rat model through inhibiting IL-6/STAT3 pathway Eman H Yousef, Nada F Abo El-Magd, Amal M El Gayar Translational Research-- 2023
3 Diosgenin potentiates the anticancer effect of doxorubicin and volasertib via regulating polo-like kinase 1 and triggering apoptosis in hepatocellular carcinoma cells Eman H Yousef , Mohamed E El-Mesery , Maha R Habeeb , Laila A Eissa Naunyn-Schmiedeberg's Archives of Pharmacology,2024
4 Revealing the association between vitamin D metabolic pathway gene variants and lung cancer risk: a systematic review and meta-analysis Mohamed I Elsalahaty, Samar Sami Alkafaas, Aya O Bashir, Khaled A El-Tarabily, Mohamed T El-Saadony , Eman H Yousef Frontiers in genetics- 2024
5 Piracetam mitigates nephrotoxicity induced by cisplatin via the AMPK-mediated PI3K/Akt and MAPK/JNK/ERK signaling pathways Ahmed M. El-Dessouki, Amany A. Alzokaky, Nahed A Raslan, Samar Ibrahim, Lamiaa A. Salama, Eman H. Yousef International Immunopharmacology Volume 137, 20 August 2024, 112511
6 Association of CTLA-4 rs733618 and rs4553808 Gene Variants with Psoriasis Vulgaris in Egyptian Population Menna M. Eldawoudy1,4*, Dalia Shaalan2, Maivel H. Ghattas3, Dina M. Abo-Elmatty4, Eman T. Mehanna Archives of Dermatological Research.2024
7 Effect of a high dose atorvastatin as added-on therapy on symptoms and serum AMPK/NLRP3 inflammasome and IL-6/STAT3 axes in patients with major depressive disorder: randomized controlled clinical study Khlood M. Aldossary, …, Amir O. Hamouda, Muhammed M. Salahuddin Front. Pharmacol., 24 May 2024
8 Correlation between depression scores and serum NF-ĸB/NLRP3 axis, biotinidase, and HMGB1 after treatment with isotretinoin in patients with acne vulgaris. Ammena Y. Binsaleh, …, Amir O. Hamouda, Muhammed M. Salahuddin J Cosmet Dermatol. 2024; 00:1–9.
9 Lead Optimization of BIBR1591 To Improve Its Telomerase Inhibitory Activity: Design and Synthesis of Novel Four Chemical Series with In Silico, In Vitro, and In Vivo Preclinical Assessments Ahmed A. Al-Karmalawy,* Amir O. Hamouda. J. Med. Chem. 2023 Vol 67/Issue 1
10 A randomized controlled trial comparing tacrolimus versus hydrocortisone for the treatment of atopic dermatitis in children: new perspectives on interferon gamma-induced protein and growth-related oncogene-α Ammena Y. Binsaleh1Amir O. Hamouda7Muhammed M. Salahuddin7 Front. Med. Volume 11 - 2024
11 Fibrosis: Types, Effects, Markers, Mechanisms for Disease Progression, and Its Relation with Oxidative Stress, Immunity, and Inflammation Samar A. Antar Nada A. Ashour Mohamed E. Marawan Ahmed A. Al-Karmalawy Int. J. Mol. Sci. 2023, 24(4), 4004;
12 Glycine is Dysregulated in Human Retinal Endothelial Cells and Proliferative Diabetic Retinopathy Andrew Gregory, Shaimaa Eltanani, Thangal Yumnamcha, Mohamed Shawky WAYNE STATE UNIVERSITY
13 Relative Contribution of Different Upper Glycolytic Components in the maintenance of the Retinal Vascular Endothelial Cell Barrier Nicole Oska, Ahmed Ibrahim, Mohamed Shawky, Diego Galarza Ramirez, Investigative Ophthalmology & Visual Science
14 The Warburg effect alters amino acid homeostasis in human retinal endothelial cells: implication for proliferative diabetic retinopathy Andrew Gregory, Thangal Yumnamcha, Mohamed Shawky, Shaimaa Eltanani Scientific Reports
15 Upper glycolytic components contribute differently in controlling retinal vascular endothelial cellular behavior: Implications for endothelial-related retinal diseases Nicole Oska, Shaimaa Eltanani, Mohamed Shawky, Armaan Naghdi Plos one
16 The Roles of Lower Glycolytic Enzymes and Transporters in Regulating the Barrier Integrity and Spreading Behavior of Retinal Endothelial Cells Nicole Barbara Oska, Shaimaa Eltanani, Mohamed Shawky, Thangal Yumnamcha Investigative Ophthalmology & Visual Science
17 Purine and pyrimidine monophosphate vs polyphosphate homeostasis in human retinal endothelial cells Andrew Gregory, Jenna Hart, Thangal Yumnamcha, Mohamed Shawky WAYNE STATE UNIVERSITY
18 The Roles of Lower Glycolytic Enzymes and Transporters in Regulating the Integrity of Retinal Vascular Endothelial Cell Barrier Nicole Oska, Shaimaa Eltanani, Mohamed Shawky, Thangal Yumnamcha, WAYNE STATE UNIVERSITY
19 Lactate/Pyruvate Regulation as a Key Determinant for Maintaining Retinal Pigment Epithelium Barrier Function: Insights from Glycolytic Screening Armaan Naghdi, Nicole Barbara Oska, Thangal Yumnamcha, Shaimaa Eltanani, Mohamed Shawky, Investigative Ophthalmology & Visual Science

Biochemistry subspeciality of Pharmacology and biochemistry department student projects

2020 - 2021

Under the Supervision Research Project
Dr. Mohamed Shawky Cytokines Storm in COVID-19; Pathogenesis and Management
Dr. Mohamed Shawky Lysosomal Storage Diseases.

Biochemistry subspeciality of Pharmacology and biochemistry department student projects

2021 - 2022

Under the Supervision Research Project
Lecturer of Biochemistry Dr. Mohamed Shawky

Assistant lecturer of biochemistry Dr. Muhammed Salahuddin
- Cisplatin induced renal injury. Role of Grape seed extract as potential therapeutic agent.
Lecturer of Biochemistry Dr. Mohamed Shawky

Assistant lecturer of biochemistry Dr. Maha Kamel
- Cisplatin induced renal injury. Role of Silymarin as potential therapeutic agent.

Biochemistry subspeciality of Pharmacology and biochemistry department student projects

2022 - 2023

Under the Supervision Research Project
Lecturer of Biochemistry Dr. Muhammed Salahuddin

Assistant lecturer Eman Hamdy Mohamed
Biochemical Effect of Ambroxol and Tadalafil on Methotrexate Induced Liver Injury in Mice
Lecturer of Biochemistry Dr. Muhammed Salahuddin

Assistant lecturer Eman Hamdy Mohamed
Biochemical Effect of Ambroxol and Tadalafil on Methotrexate Induced kidney Injury in Mice

Prof. Dr. Magda Nasr

Vice President & Faculty Dean

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