Analytical Chemistry

Publications

Publications and Year Name
1. Carbon quantum dots as nanosensors for the spectrofluorimetric determination of meloxicam in biological fluids and dosage forms: Greenness assessment and application to content uniformity testing. https://doi.org/10.1016/j.scp.2024.101691

2. First derivative synchronous spectrofluorimetric method for the simultaneous determination of tramadol and celecoxib in their dosage forms and human plasma. https://doi.org/10.1002/bio.4774

3. Simultaneous estimation of two anti-diabetic drugs; Linagliptin and empagliflozin in their tablet by chemometric spectrophotometry.

4. Study of the binding interaction of salmon sperm DNA with nintedanib, a tyrosine kinase inhibitor using multi-spectroscopic, thermodynamic, and in silico approaches. https://doi.org/10.1080/07391102.2023.2202776

5.Spectral resolving of propofol and benzyl alcohol mixture. https://doi.org/10.21608/RPBS.2023.237410.1243

6. Eco-friendly simultaneous multi-spectrophotometric estimation of the newly approved drug combination of celecoxib and tramadol hydrochloride tablets in its dosage form. https: doi.org/10.1038/s41598-023-38702-9

7. Deduction of the operable design space of RP-HPLC technique for the simultaneous estimation of metformin, pioglitazone, and glimepiride. https://doi.org/10.1038/s41598-023-30051-x

8. Green fluorometric strategy for simultaneous determination of the antihypertensive drug telmisartan (A tentative therapeutic for COVID-19) with Nebivolol in human plasma. https://doi.org/10.1038/s41598-023-30400-w

9. Study of the binding interaction of salmon sperm DNA with nintedanib, a tyrosine kinase inhibitor using multi-spectroscopic, thermodynamic, and in silico approaches AS Radwan, MM Salim, MM Elkhoudary, GM Hadad, Moataz A Shaldam, Fathalla Belal, Galal Magdy Journal of Biomolecular Structure and Dynamics, 2023, 1-11.

10. Deduction of the operable design space of RP-HPLC technique for the simultaneous estimation of metformin, pioglitazone, and glimepiride Marie, A.A., Hammad, S.F., Salim, M.M., Elkhodary, M.M., Kamal, A.H. Scientific Reports, 2023, 13(1), 4334.

11. Green fluorometric strategy for simultaneous determination of the antihypertensive drug telmisartan (A tentative therapeutic for COVID-19) with Nebivolol in human plasma MM Salim, A Radwan, GM Hadad, F Belal, MM Elkhoudary Scientific Reports 13 (1), 3576.

12. Using of eosin Y as a facile fluorescence probe in alogliptin estimation: Application to tablet dosage forms and content uniformity testing MM Salim, AA Marie, AH Kamal, SF Hammad, MM Elkhoudary Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 285, 121919 .

13. Voltammetric estimation of residual nitroxynil in food products using carbon paste electrode M. M. Salim, S Ashraf, H. M. Hashem, F Belal Scientific Reports, 12 (2022), 14289.

14. Analytical quality by design based on design space in reversedphase-high performance liquid chromatography analysis for simultaneous estimation of metformin, linagliptin and empagliflozin A. A. Marie, M. M. Salim, A. H. Kamal, S. F. Hammad and M. M. Elkhoudary Royal Society Open Science 9(6), (2022) 220215.

15. A highly sensitive spectrofluorimetric method for the determination of bilastine in its pharmaceutical preparations and biological fluids A saad Radwan, MM Elkhoudary, GM Hadad, F Belal, M.M. Salim 10 Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 276 (2022), 121246.

16. Spectrofluorometric determination of residual amounts of nitroxynil in food samples S Ashraf, F Belal, M. M. Salim Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 274(2022), 120993.

17. Analytical approaches for the determination of Nebivolol A Radwan, MM Salim, MM Elkhoudary, G Hadad, F Belal Records of Pharmaceutical and Biomedical Sciences 6 (2022), 113-119.

18. Simultaneous estimation of recently FDA approved co-formulated ophthalmic solution benoxinate and fluorescein: Application to aqueous humor AS Radwan, M. M. Salim, GM Hadad, F Belal, MM Elkhoudary Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 267 (2022), 120599.

19. Eco-friendly fluorimetric approaches for the simultaneous estimation of the co-administered ternary mixture: etoposide, moxifloxacin, and nalbuphine M. Tolba, F. Belal and M. M. Salim Royal Society Open Science 8(9), (2021) 210683. [DOI: 10.1098/rsos.210683]

20. Insights for applying erythrosine B as a green fluorescence probe for estimation of anticancer tamoxifen and its analog; clomiphene in nanogram concentration. M. Tolba and M. M. Salim Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 263 (2021), 120156. [DOI: 10.1016/j.saa.2021.120156]

21. Gastroenterology manifestations and COVID-19 outcomes: A meta-analysis of 25,252 cohorts among the first and second waves Rami M. Elshazli, Adam Kline, Abdelaziz Elgaml, Mohamed H. Aboutaleb, Mohamed M. Salim, Mahmoud Omar, Ruhul Munshi, Nicholas Mankowski, Mohammad H. Hussein, Abdallah S. Attia,Eman A. Toraih, Ahmad Settin, Mary Killackey, Manal S. Fawzy, Emad Kandil Medical Virology, 93 (2021) 2740-2768 [DOI:10.1002/jmv.26836].

22. Simultaneous estimation of troxerutin and calcium dobesilate in presence of the carcinogenic hydroquinone using green spectrofluorimetric method. M. M. Tolba, M. M. Salim and M. El-Awady 11 Royal Society Open Science 8(2), (2021) 201888. [DOI: 10.1098/rsos.201888]

23. Multi-spectroscopic and molecular docking studies for binding interaction between fluvoxamine and human serum albumin M. M. Salim, Mona E. El Sharkasy, F. Belal and M. Walash Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 252 (2021) 119495 [DOI: 10.1016/j.saa.2021.119495]

24. Inclusive study for segregation of two commonly used anticancer drugs with tramadol: Applying a green fluorimetric strategy to pharmaceutical dosage forms and human plasma M. Tolba and M. M. Salim Microchemical Journal. 162 (2021) 105859 [DOI: 10.1016/j.microc.2020.105859]

25. Genetic Algorithm with Model-Updating Based PLS Regression for the Spectrophotometric Determination of Clopidogrel, Atorvastatin and Aspirin in presence of its degradation product. M. M. Salim, Mona E. El Sharkasy, M. Walash and F. Belal Journal of Applied Spectroscopy 2020, 87 (3), 509-519.

26. Synchronous spectrofluorometric methods for simultaneous determination of diphenhydramine and ibuprofen or phenylephrine in combined pharmaceutical preparations. Aya S Radwan, M. M. Salim and Sherin Hammad Luminescence. 2020,35, 550–560. [DOI: 10.1002/bio.3750]

27. Conventional and first derivative synchronous spectrofluorimetric methods for the simultaneous determination of cisatracurium and nalbuphine in biological fluids. Mona E. El Sharkasy, M.

Walash, F. Belal, M.M. Salim. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2020, 228, 117841 [DOI:10.1016/j.saa.2019.117841]

28. First derivative synchronous spectrofluorimetric method for the simultaneous determination of propofol and cisatracurium besylate in biological fluids. Mona E. El Sharkasy, M. Walash, F. Belal and M.M. Salim. Luminescence. 2020, 35, 312–320 [DOI: 10.1002/bio.3729]

29. Derivative Quotient Spectrophotometry and an Eco-Friendly Micellar Chromatographic Approach with Time-Programmed UVDetection for the Separation of Two Fluoroquinolones and Phenazopyridine. Manar M. Tolba and M. M. Salim. J Chromatogr Sci 2016, 54(5), 776-789 12 [DOI: 10.1093/chromsci/bmw010]

30. Simultaneous determination of valsartan, amlodipine besylate and hydrochlorothiazide using capillary zone electrophoresis (CZE). W. Ebeid, M.M. Salim, E. Elkady, A. Elzahr, R. El-Bagary and G. Patonay. Die Pharmazie 2015, 70, 368–373. [DOI: 10.1691/ph.2015.4134]

31. Hydroxylated near-infrared BODIPY fluorophores as intracellular pH sensors. M. M. Salim, E. A. Owens, T. Gao, J. H. Lee, H. Hyun, H. S. Choi and M. Henary. Analyst. 2014, 139, 4862-4873. [DOI: 10.1039/c4an01104j]

32. Simultaneous determination of aliskiren hemifumarate, amlodipine besylate, and hydrochlorothiazide in their triple mixture dosage form by capillary zone electrophoresis. M. M. Salim, W. M. Ebeid, N. El-Enany, F. Belal, M. Walash and G. Patonay. J Sep Sci. 2014, 37, 1206-1213. [DOI: 10.1002/jssc.201301140]

33. Micelle-enhanced spectrofluorimetric method for determination of sitagliptin and identification of potential alkaline degradation products using LC-MS. M. M. Salim, N. El-Enany, F. Belal, M. Walash and G. Patonay. Luminescence. 2014, 29, 65-73. [DOI: 10.1002/bio.2503]

34. Simultaneous Determination of Sitagliptin and Metformin in Pharmaceutical Preparations by Capillary Zone Electrophoresis and its Application to Human Plasma Analysis. M. M. Salim, N. El-Enany, F. Belal, M. Walash and G. Patonay. Anal. Chem. Insights 2012, 7, 31-46. [DOI: 10.4137/ACI.S9940]

35. Derivative Spectrophotometric Analysis of Benzophenone (as an impurity) in Phenytoin. M.I. Walash, M. Rizk, Z.A. Sheribah, M.M. Salim. Chemistry Central Journal 2011, 5(1), 85. [DOI: 10.1186/1752-153X-5-85]

36. Development and Validation of Spectrofluorimetric Method for Determination of Biotin in Bulk and Pharmaceutical preparations via its oxidation with cerium (IV). M.I. Walash, M. Rizk, Z.A. Sheribah, M.M. Salim. Int. J. Biomed. Sci. 2010, 6(3), 268.

37. Kinetic Spectrophotometric Determination of Biotin in Pharmaceutical Preparations. M.I. Walash, M. Rizk, Z.A. 13 Sheribah, M.M. Salim. Int. J. Biomed. Sci. 2008, 4(3), 238.
Assoc. Prof. Mohamed M. Salim
1. Radwan AS, Salim MM, Elkhoudary MM, Hadad GM, Shaldam MA, Belal F, Magdy G: Study of the binding interaction of salmon sperm DNA with nintedanib, a tyrosine kinase inhibitor using multi-spectroscopic, thermodynamic, and in silico approaches. Journal of Biomolecular Structure and Dynamics 2024, 42(3):1170- 1180.

2. Radwan AS, Magdy G, Belal F, Hadad GM, Elkhoudary MM, Salim MM: Carbon quantum dots as nanosensors for the spectrofluorimetric determination of meloxicam in biological fluids and dosage forms: Greenness assessment and application to content uniformity testing. Sustainable Chemistry and Pharmacy 2024, 41:101691.


4. Salim MM, Radwan As, Hadad GM, Belal F, Elkhoudary MM: Green fluorometric strategy for simultaneous determination of the antihypertensive drug telmisartan (A tentative therapeutic for COVID-19) with Nebivolol in human plasma. Scientific Reports 2023, 13(1):3576.

5. Salim MM, Marie AA, Kamal AH, Hammad SF, Elkhoudary MM: Using of eosin Y as a facile fluorescence probe in alogliptin estimation: Application to tablet dosage forms and content uniformity testing. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 2023, 285:121919.

6. Marie AA, Hammad SF, Salim MM, Elkhodary MM, Kamal AH: Deduction of the operable design space of RP-HPLC technique for the simultaneous estimation of metformin, pioglitazone, and glimepiride. Scientific reports 2023, 13(1):4334.

7. ELshreif HM, Elkhoudary MM, Moustafa R, Hadad G, El-Gendy A: A review on food additives from the definition, and types to the method of analysis. Records of Pharmaceutical and Biomedical Sciences 2023, 7(1):48-64.

8. Elkhoudary MM: Mohamed M. Salim, Aya saad Radwan, Ghada M. Hadad, Fathalla Belal &. Scientific Reports 2023, 13:3576.

9. Selim BM, Abdelsalam RA, El-Gindy A, Eid BG, Neamatallah T, Khayyat AN, Hadad GM, Elkhoudary MM: A green approach to the analysis of co-administered ampicillin/sulbactam and paracetamol in human urine. Acta Pharmaceutica 2022, 72(2):259-274.

10. Radwan AS, Salim MM, Hadad GM, Belal F, Elkhoudary MM: Simultaneous estimation of recently FDA approved co-formulated ophthalmic solution benoxinate and fluorescein: Application to aqueous humor. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 2022, 267:120599.

11. Radwan AS, Elkhoudary MM, Hadad GM, Belal F, Salim MM: A highly sensitive spectrofluorimetric method for the determination of bilastine in its pharmaceutical preparations and biological fluids. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 2022, 276:121246.

12. Radwan A, Salim MM, Elkhoudary MM, Hadad G, Belal F: Analytical approaches for the determination of Nebivolol. Records of Pharmaceutical and Biomedical Sciences 2022, 6(1):113-119

13. Marie AA, Salim MM, Kamal AH, Hammad SF, Elkhoudary MM: Analytical quality by design based on design space in reversed-phase-high performance liquid chromatography analysis for simultaneous estimation of metformin, linagliptin and empagliflozin. Royal Society Open Science 2022, 9(6):220215.

14. Elkhoudary MM: Aya A. Marie1, 3, Mohamed M. Salim1, 2, Amira H. Kamal3, Sherin F. Hammad3 and. 2022.

15. Mazyed EA, Helal DA, Elkhoudary MM, Abd Elhameed AG, Yasser M: Formulation and optimization of nanospanlastics for improving the bioavailability of green tea epigallocatechin gallate. Pharmaceuticals 2021, 14(1):68.

16. Hassan TH, Salman SS, Elkhoudary MM, Gad S: Refinement of Simvastatin and Nifedipine combined delivery through multivariate conceptualization and optimization of the nanostructured lipid carriers. Journal of Drug Delivery Science and Technology 2021, 64:102570.

17. Ghanem HA, Nasr AM, Hassan TH, Elkhoudary MM, Alshaman R, Alattar A, Gad S: Comprehensive study of atorvastatin nanostructured lipid carriers through multivariate conceptualization and optimization. Pharmaceutics 2021, 13(2):178.

18. Diab MA, Ibrahim AK, Hadad GM, Elkhoudary MM: Seasonal variations in antioxidant components of Olea europaea in leaves of different cultivars, seasons, and oil products in Sinai. Food Analytical Methods 2021, 14:773-783.

19. Nasr AM, Qushawy MK, Elkhoudary MM, Gawish AY, Elhady SS, Swidan SA: Quality by design for the development and analysis of enhanced in-situ forming vesicles for the improvement of the bioavailability of fexofenadine HCl in vitro and in vivo. Pharmaceutics 2020, 12(5):409.

20. Elkhoudary MM, Selim BM, AbdelSalam RA, Hadad GM, El-Gindy A: Development and validation of a simple HPTLC method for the determination of new hepatitis C subtype 4 antiviral agents in their tablet dosage form. JPC–Journal of Planar Chromatography–Modern TLC 2020, 33:71-77.

21. Elkhoudary MM, Salam RAA, Hadad GM: Resolution and quantification challenge of modern chemometric models in the determination of anti-migraine tablets containing ergotamine, caffeine, acetaminophen, and metoclopramide. Rsc advances 2017, 7(34):20936-20946

22. Elkhoudary MM, Naguib IA, Abdel Salam RA, Hadad GM: Comparison between two linear supervised learning machines’ methods with principle component based methods for the spectrofluorimetric determination of agomelatine and its degradants. Journal of fluorescence 2017, 27:1149-1160.

23. Elkhoudary MM, Abdel Salam RA, Hadad GM: Development and optimization of HPLC analysis of metronidazole, diloxanide, spiramycin and cliquinol in pharmaceutical dosage forms using experimental design. Journal of chromatographic science 2016, 54(10):1701-1712.

24. Hadad G, Salam RA, Elkhoudary MM: Simultaneous determination of clarithromycin, tinidazole and omeprazole in helicure tablets using reflectance near-infrared spectroscopy with the aid of chemometry. Pharmaceutica Analytica Acta 2015, 6(4):10.4172.

25. Elkhoudary MM, Abdel Salam RA, Hadad GM: Stability-indicating methods for determination of flubendazole and its degradants. Journal of chromatographic science 2015, 53(6):915-924.

26. Elkhoudary MM, Abdel Salam RA, Hadad GM: Robustness testing in HPLC analysis of clarithromycin, norfloxacin, doxycycline, tinidazole and omeprazole in pharmaceutical dosage forms using experimental design. Current Pharmaceutical Analysis 2014, 10(1):58-70.

27. Elkhoudary MM, Salam RAA, Hadad GM: Comparative artificial neural network and partial least squares models for analysis of Metronidazole, Diloxanide, Spiramycin and Cliquinol in pharmaceutical preparations. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 2014, 130:222-229.
Assoc. Prof. Mahmoud Medhat Ibrahim Elkhoudary
Publisher  Author Title
Royal Society Open Science Aya Abu El-enien Marie Analytical quality by design based on design space in reversed-phase-high performance liquid chromatography analysis for simultaneous estimation of metformin, linagliptin and empagliflozin
Spectrochimica Acta - Part A Aya Abu El-enien Marie Using of eosin Y as a facile fluorescence probe in alogliptin estimation: Application to tablet dosage forms and content uniformity testing
Scientific Reports Aya Abu El-enien Marie Deduction of the operable design space of RP-HPLC technique for the simultaneous estimation of metformin, pioglitazone, and glimepiride
Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy Aya Abu El-enien Marie Simultaneous estimation of two anti-diabetic drugs; Linagliptin and empagliflozin in their tablet by chemometric spectrophotometry.
Scientific Reports Aya saad radwan Green fluorometric strategy for simultaneous determination of the antihypertensive drug telmisartan (A tentative therapeutic for COVID-19) with Nebivolol in human plasma
Spectrochimica Acta Part A Aya saad radwan A highly sensitive spectrofluorimetric method for the determination of bilastine in its pharmaceutical preparations and biological fluids
Spectrochimica Acta Part A Aya saad radwan Simultaneous estimation of recently FDA approved co-formulated ophthalmic solution benoxinate and fluorescein: Application to aqueous humor
Journal of Biomolecular Structure and Dynamics Aya saad radwan Study of the binding interaction of salmon sperm DNA with nintedanib, a tyrosine kinase inhibitor using multi-spectroscopic, thermodynamic, and in silico approaches
Records of Pharmaceutical and Biomedical Sciences Aya saad radwan Analytical approaches for the determination of Nebivolol
Journal of Fluorescence Aya rosdy fouda A Design-assisted Spectrofluorometric Method Utilizing a One-pot Fluorescent Probe for the Quantitation of some Calcium Channel Blockers
BMC Chemistry Aya rosdy fouda Green quality by design HPLC approach for the simultaneous determination of Bilastine and Montelukast
Journal of Fluorescence Aya roshdy fouda A Design-assisted Spectrofluorometric Method Utilizing a One-pot Fluorescent Probe for the Quantitation of some Calcium Channel Blockers.
BMC Chemistry Aya roshdy fouda Green quality by design HPLC approach for the simultaneous determination of Bilastine and Montelukast.
Luminescence Aya roshdy fouda Fast concurrent determination of guaifenesin and pholcodine in formulations and spiked plasma using first derivative synchronous spectrofluorimetric approach
Publications and Year Name
1- A Gadolinium-Based Magnetic Ionic Liquid for Dispersive Liquid-Liquid Microextraction of Ivermectin from Environmental Water.

2- Spectrofluorometric Determination of Baricitinib in Pure Form and Application on Pharmaceutical Dosage Form; Green Profile Evaluation via Eco-scale and GAPI Tools.

3- UV Spectrophotometric Method Development and Validation of Vonoprazan Fumarate in Bulk and Pharmaceutical Dosage form; Green Profile Evaluation Via eco-scale And GAPI Tools.

4- Nanobiosensors: A powerful Technology for Early Detection of Plant Parasitic Nematodes. https://doi.org/10.1007/s11220-024-00470-9

5- Genetic Improvement of Small Millets. Chapter 13th. https://doi.org/10.1007/978-981-99-7232-6
TA. Ahmed Mohamed Saleh
1- First derivative synchronous spectrofluorimetric method for the simultaneous determination of tramadol and celecoxib in their dosage forms and human plasma

2- Spectral resolving of propofol and benzyl alcohol mixture

3- Eco-friendly simultaneous multi-spectrophotometric estimation of the newly approved drug combination of celecoxib and tramadol hydrochloride tablets in its dosage form
TA. Hesham Sameh Ramadan
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