التخصص العلمي الكيمياء الحيوية
أ. د. ماجدة نصر
نائب رئيس الجامعة وعميد الكلية
نرحب بكل من يساهم في بناء مستقبل وطننا لمساعدته على أن يأخذ مكانة مميزة بين الأمم.
مقررات الكيمياء الحيوية
الأبحاث الحديثة المنشورة في المؤتمرات والمجلات المحلية والعالمية
2018 - 2020
| # | عنوان البحث | المؤلف | جهة النشر |
|---|---|---|---|
| 1 | Evaluation of the antirheumatic effects of isoflavone-free soy protein isolate and etanercept in rats with adjuvant-induced arthritis | El-Ashmawy N E, Khedr E G, Shamloula M M, and Kamel M M | Experimental Biology and Medicine 244(7):545-553. |
| 2 | Genetic polymorphisms of IL-17A rs2275913, rs3748067 and IL-17F rs763780 in gastric cancer risk: evidence from 8124 cases and 9873 controls. | Elshazli R M, Salman D O, Kamel M M, Toraih E A, and Fawzy M S | Molecular Biology Reports 45(5):1421-1444. |
| 3 | Association Between Soluble Urokinase Plasminogen Activator Receptor And Interleukin 6 In The Diagnosis Of Coronary Artery Disease Patients | Nahla E El-Ashmawy, Eman G Khedr, Awad M ElAbd, Amir O Hamouda | |
| 4 | Polo-like kinase 1 as a promising diagnostic biomarker and potential therapeutic target for hepatocellular carcinoma | Yousef, Eman H; El-Mesery, Mohamed E; Habeeb, Maha R; Eissa, Laila A; | Tumor Biology, 4(42): 1010430000000000 |
الأبحاث الحديثة المنشورة في المؤتمرات والمجلات المحلية والعالمية
2021 - 2022
| # | عنوان البحث | المؤلف | جهة النشر |
|---|---|---|---|
| 1 | Lactoferrin Ameliorates Azithromycin-induced Cardiac Injury: Insight into Oxidative Stress/TLR4/NF-κB Pathway | Helal, Manar; Shawky, Mohamed; Elhusseiny, Shady; Abd Elhameed, Ahmed; | Journal of Advanced Pharmacy Research |
| 2 | 10-Dehydrogingerdione ameliorates renal endoplasmic reticulum/oxidative stress and apoptosis in alcoholic nephropathy induced in experimental rats. | Elnagar G M, Elseweidy M M, Mahmoud Y K, Elkomy N M, Althafar Z M, Alnomasy S F, Al-Gabri N A, and Shawky M | Life Sciences, 279:119673. |
| 3 | Effect of regorafenib on P2X7 receptor expression and different oncogenic signaling pathways in a human breast cancer cell line: a potential of new insight of the antitumor effects of regorafenib. | Salahuddin M M, Omran G A, Helmy M W, and Houssen M E | Current Issues in Molecular Biology 43(3):2199-2209. |
| 4 | Lactoferrin Ameliorates Azithromycin-induced Cardiac Injury: Insight into Oxidative Stress/TLR4 /NF-κB Pathway | Manar G. Helal, Mohamed Shawky, Shady Elhusseiny, Ahmed G. Abd Elhameed | Journal of Advanced Pharmacy Research, 2021, 5 (2), 273-284 |
الأبحاث الحديثة المنشورة في المؤتمرات والمجلات المحلية والعالمية
2022 - 2023
| # | عنوان البحث | المؤلف | جهة النشر |
|---|---|---|---|
| 1 | Pentoxifylline and its association with kaempferol improve NASH-associated manifestation in mice through anti-apoptotic, anti-necroptotic, antioxidant, and anti-inflammatory mechanisms. | Hamouda A, Abdel-Hamed A, Abo-Elmatty D, Khedr N, and Ghattas M | European Review for Medical and Pharmacological Sciences 26(23):8644-8659 |
| 2 | Role of Kaempferol Combined with Pioglitazone in the Alleviation of Inflammation and Modulation of Necroptosis and Apoptosis Pathways in NASH-induced Mice . | Maivel H. Ghattas Asmaa R. Abdel-Hamed, Amir O. Hamouda, Dina M. Abo-elmatty, Naglaa F. Khedr | Journal of Medicinal and Chemical Sciences 6(5):250-265 |
| 3 | 10-Dehydrogingerdione Attenuates Tramadol-Induced Nephrotoxicity by Modulating Renal Oxidative Stress, Inflammation and Apoptosis in Experimental Rats: Role of HO-1 Activation and TLR4/NF-κB/ERK Inhibition. | Elnagar G M, Elseweidy M M, Mahmoud Y K, Elkomy N M, Althafar Z M, Alnomasy S F, Al-Gabri N A, and Shawky M | international Journal of Molecular Sciences 23(3):1384 |
| 4 | Relative Importance of Different Elements of Mitochondrial Oxidative Phosphorylation in Maintaining the Barrier Integrity of Retinal Endothelial Cells: Implications for Vascular-Associated Retinal Diseases. , ... | Elnagar G M, Elseweidy M M, Mahmoud Y K, Elkomy N M, Althafar Z M, Alnomasy S F, Al-Gabri N A, and Shawky M | Cells 11(24):4128. |
| 5 | Fibrosis: Types, Effects, Markers, Mechanisms for Disease Progression, and Its Relation with Oxidative Stress, Immunity, and Inflammation. | Antar SA, Ashour NA, Marawan ME, Al-Karmalawy AA. | International Journal of Molecular Sciences. 2023;24:4004. |
الأبحاث الحديثة المنشورة في المؤتمرات والمجلات المحلية والعالمية
2023 - 2024
| # | عنوان البحث | المؤلف | جهة النشر |
|---|---|---|---|
| 1 | Life Sciences, -2023 | Eman H Yousef, Nada F Abo El-Magd, Amal M El Gayar | Carvacrol enhances anti-tumor activity and mitigates cardiotoxicity of sorafenib in thioacetamide-induced hepatocellular carcinoma model through inhibiting TRPM7 |
| 2 | Translational Research-- 2023 | Eman H Yousef, Nada F Abo El-Magd, Amal M El Gayar | Norcantharidin potentiates sorafenib antitumor activity in hepatocellular carcinoma rat model through inhibiting IL-6/STAT3 pathway |
| 3 | Naunyn-Schmiedeberg's Archives of Pharmacology,2024 | Eman H Yousef , Mohamed E El-Mesery , Maha R Habeeb , Laila A Eissa | Diosgenin potentiates the anticancer effect of doxorubicin and volasertib via regulating polo-like kinase 1 and triggering apoptosis in hepatocellular carcinoma cells |
| 4 | Frontiers in genetics- 2024 | Mohamed I Elsalahaty, Samar Sami Alkafaas, Aya O Bashir, Khaled A El-Tarabily, Mohamed T El-Saadony , Eman H Yousef | Revealing the association between vitamin D metabolic pathway gene variants and lung cancer risk: a systematic review and meta-analysis |
| 5 | International Immunopharmacology Volume 137, 20 August 2024, 112511 | Ahmed M. El-Dessouki, Amany A. Alzokaky, Nahed A Raslan, Samar Ibrahim, Lamiaa A. Salama, Eman H. Yousef | Piracetam mitigates nephrotoxicity induced by cisplatin via the AMPK-mediated PI3K/Akt and MAPK/JNK/ERK signaling pathways |
| 6 | Archives of Dermatological Research.2024 | Menna M. Eldawoudy1,4*, Dalia Shaalan2, Maivel H. Ghattas3, Dina M. Abo-Elmatty4, Eman T. Mehanna | Association of CTLA-4 rs733618 and rs4553808 Gene Variants with Psoriasis Vulgaris in Egyptian Population |
| 7 | Front. Pharmacol., 24 May 2024 | Khlood M. Aldossary, …, Amir O. Hamouda, Muhammed M. Salahuddin | Effect of a high dose atorvastatin as added-on therapy on symptoms and serum AMPK/NLRP3 inflammasome and IL-6/STAT3 axes in patients with major depressive disorder: randomized controlled clinical study |
| 8 | J Cosmet Dermatol. 2024; 00:1–9. | Ammena Y. Binsaleh, …, Amir O. Hamouda, Muhammed M. Salahuddin | Correlation between depression scores and serum NF-ĸB/NLRP3 axis, biotinidase, and HMGB1 after treatment with isotretinoin in patients with acne vulgaris. |
| 9 | J. Med. Chem. 2023 Vol 67/Issue 1 | Ahmed A. Al-Karmalawy,* Amir O. Hamouda. | Lead Optimization of BIBR1591 To Improve Its Telomerase Inhibitory Activity: Design and Synthesis of Novel Four Chemical Series with In Silico, In Vitro, and In Vivo Preclinical Assessments |
| 10 | Front. Med. Volume 11 - 2024 | Ammena Y. Binsaleh1Amir O. Hamouda7Muhammed M. Salahuddin7 | A randomized controlled trial comparing tacrolimus versus hydrocortisone for the treatment of atopic dermatitis in children: new perspectives on interferon gamma-induced protein and growth-related oncogene-α |
| 11 | Int. J. Mol. Sci. 2023, 24(4), 4004; | Samar A. Antar Nada A. Ashour Mohamed E. Marawan Ahmed A. Al-Karmalawy | Fibrosis: Types, Effects, Markers, Mechanisms for Disease Progression, and Its Relation with Oxidative Stress, Immunity, and Inflammation |
| 12 | WAYNE STATE UNIVERSITY | Andrew Gregory, Shaimaa Eltanani, Thangal Yumnamcha, Mohamed Shawky | Glycine is Dysregulated in Human Retinal Endothelial Cells and Proliferative Diabetic Retinopathy |
| 13 | Investigative Ophthalmology & Visual Science | Nicole Oska, Ahmed Ibrahim, Mohamed Shawky, Diego Galarza Ramirez, | Relative Contribution of Different Upper Glycolytic Components in the maintenance of the Retinal Vascular Endothelial Cell Barrier |
| 14 | Scientific Reports | Andrew Gregory, Thangal Yumnamcha, Mohamed Shawky, Shaimaa Eltanani | The Warburg effect alters amino acid homeostasis in human retinal endothelial cells: implication for proliferative diabetic retinopathy |
| 15 | Plos one | Nicole Oska, Shaimaa Eltanani, Mohamed Shawky, Armaan Naghdi | Upper glycolytic components contribute differently in controlling retinal vascular endothelial cellular behavior: Implications for endothelial-related retinal diseases |
| 16 | Investigative Ophthalmology & Visual Science | Nicole Barbara Oska, Shaimaa Eltanani, Mohamed Shawky, Thangal Yumnamcha | The Roles of Lower Glycolytic Enzymes and Transporters in Regulating the Barrier Integrity and Spreading Behavior of Retinal Endothelial Cells |
| 17 | WAYNE STATE UNIVERSITY | Andrew Gregory, Jenna Hart, Thangal Yumnamcha, Mohamed Shawky | Purine and pyrimidine monophosphate vs polyphosphate homeostasis in human retinal endothelial cells |
| 18 | WAYNE STATE UNIVERSITY | Nicole Oska, Shaimaa Eltanani, Mohamed Shawky, Thangal Yumnamcha, | The Roles of Lower Glycolytic Enzymes and Transporters in Regulating the Integrity of Retinal Vascular Endothelial Cell Barrier |
| 19 | Investigative Ophthalmology & Visual Science | Armaan Naghdi, Nicole Barbara Oska, Thangal Yumnamcha, Shaimaa Eltanani, Mohamed Shawky, | Lactate/Pyruvate Regulation as a Key Determinant for Maintaining Retinal Pigment Epithelium Barrier Function: Insights from Glycolytic Screening |
المشاريع البحثية لتخصص الكيمياء الحيوية لقسم الأدوية و الكيمياء الحيوية بكلية الصيدلة جامعة حورس
2020 - 2021
| مشروع البحث | تحت إشراف |
|---|---|
| Cytokines Storm in COVID-19; Pathogenesis and Management | Dr. Mohamed Shawky |
| Lysosomal Storage Diseases | Dr. Mohamed Shawky |
| # | عنوان البحث | المؤلف | جهة النشر |
|---|---|---|---|
| 1 | Evaluation of the antirheumatic effects of isoflavone-free soy protein isolate and etanercept in rats with adjuvant-induced arthritis | El-Ashmawy N E, Khedr E G, Shamloula M M, and Kamel M M | Experimental Biology and Medicine 244(7):545-553. |
| 2 | Genetic polymorphisms of IL-17A rs2275913, rs3748067 and IL-17F rs763780 in gastric cancer risk: evidence from 8124 cases and 9873 controls. | Elshazli R M, Salman D O, Kamel M M, Toraih E A, and Fawzy M S | Molecular Biology Reports 45(5):1421-1444. |
| 3 | Association Between Soluble Urokinase Plasminogen Activator Receptor And Interleukin 6 In The Diagnosis Of Coronary Artery Disease Patients | Nahla E El-Ashmawy, Eman G Khedr, Awad M ElAbd, Amir O Hamouda | |
| 4 | Polo-like kinase 1 as a promising diagnostic biomarker and potential therapeutic target for hepatocellular carcinoma | Yousef, Eman H; El-Mesery, Mohamed E; Habeeb, Maha R; Eissa, Laila A; | Tumor Biology, 4(42): 1010430000000000 |
المشاريع البحثية لتخصص الكيمياء الحيوية لقسم الأدوية و الكيمياء الحيوية بكلية الصيدلة جامعة حورس
2021 - 2022
| مشروع البحث | تحت إشراف |
|---|---|
| - Cisplatin induced renal injury. Role of Grape seed extract as potential therapeutic agent | Lecturer of Biochemistry Dr. Mohamed Shawky Assistant lecturer of biochemistry Dr. Muhammed Salahuddin |
| - Cisplatin induced renal injury. Role of Silymarin as potential therapeutic agent | Lecturer of Biochemistry Dr. Mohamed Shawky Assistant lecturer of biochemistry Dr. Maha Kamel |
المشاريع البحثية لتخصص الكيمياء الحيوية لقسم الأدوية و الكيمياء الحيوية بكلية الصيدلة جامعة حورس
2022 - 2023
| مشروع البحث | تحت إشراف |
|---|---|
| Biochemical Effect of Ambroxol and Tadalafil on Methotrexate Induced Liver Injury in Mice | Lecturer of Biochemistry Dr. Muhammed Salahuddin Assistant lecturer Eman Hamdy Mohamed |
| Biochemical Effect of Ambroxol and Tadalafil on Methotrexate Induced kidney Injury in Mice | Lecturer of Biochemistry Dr. Muhammed Salahuddin Assistant lecturer Eman Hamdy Mohamed |
